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5-HMF For Functional Feed Additives Wholesale

5-HMF For Functional Feed Additives

High-purity targeted bio-active compound — engineered for cellular antioxidant defense, metabolic liver health, and gut protection.
CAS 67-47-0 · Molecular Formula C₆H₆O₃ · MW 126.11
Purity

≥ 98.0%

  • HPLC Purity 98.5%
  • Moisture content ≤ 1.0%
  • Heavy metals (Pb) ≤ 3 ppm
Physical

Micro-crystalline

  • Melting point 32 – 35 °C
  • Water solubility 100% Dissolvable
  • Thermal endurance Stable to 100°C
Functional Performance

Multi-Target Grade

  • Inclusion rate 50 – 300 g/t
  • pH (1% soln) 4.5 – 6.5
  • Shelf life 24 Months
5- Hydroxymethylfurfural (HMF)

5- Hydroxymethylfurfural (HMF)

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2, 5- Furandicarboxylic acid (FDCA)

2, 5- Furandicarboxylic acid (FDCA)

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2, 5- Furandicarboxylicacid dimethyl ester (FDME)

2, 5- Furandicarboxylicacid dimethyl ester (FDME)

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Poly (ethylene 2,5-furandicarboxylate) (PEF)

Poly (ethylene 2,5-furandicarboxylate) (PEF)

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2,5- Furandiyldimethanol (FDM)

2,5- Furandiyldimethanol (FDM)

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2, 5- Tetrahydrofuran dimethanol (THFDM)

2, 5- Tetrahydrofuran dimethanol (THFDM)

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2, 5- Bis (aminomethyl) tetrahydrofuran (BAMTHF)

2, 5- Bis (aminomethyl) tetrahydrofuran (BAMTHF)

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2, 5- Tetrahydrofuran dicarboxylic acid (THFDCA)

2, 5- Tetrahydrofuran dicarboxylic acid (THFDCA)

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5, 5' (oxy- bis (methylene) ) bis- 2- furfural (OBMF)

5, 5' (oxy- bis (methylene) ) bis- 2- furfural (OBMF)

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Product Overview

5-Hydroxymethylfurfural (5-HMF) for Functional Feed Additives is a high-potency bio-active compound manufactured by Zhejiang Sugar Energy Technology Co., Ltd. Designed specifically for animal nutritionists, specialty premix integrators, and feed additive innovators, this bio-derived active compound serves as a targeted functional agent for cellular stress mitigation, hepatopancreas and metabolic liver protection, and gut mucosal barrier fortification across multi-species commercial feeds.

Modern intensive livestock and aquaculture production requires functional feed additives that go beyond simple macronutrient supply to actively protect physiological health. Farm animals constantly experience metabolic challenges, environmental heat stress, high stocking density, and inflammatory gut erosion. 5-HMF fulfills this demand by acting as a direct cellular free-radical scavenger, neutralizing intracellular reactive oxygen species (ROS) and maintaining metabolic homeostasis.

Synthesized from renewable C6 plant carbohydrate biomass through green catalytic chemistry, our functional-grade 5-HMF features a verified chemical purity exceeding 98.0%. When incorporated into specialized functional premixes at 50 to 300 grams per metric ton of complete feed, 5-HMF repairs tight junction proteins (occludin and claudin-1), reduces serum liver enzyme markers, preserves small intestinal microvilli height, and lowers overall Feed Conversion Ratio (FCR) in poultry, swine, ruminants, and aquatic species.

Zhejiang Sugar Energy Technology Co., Ltd. operates under strict ISO 9001 and ISO 22000 / GMP quality management systems, ensuring zero heavy metal contamination (Pb ≤ 3 ppm, As/Cd ≤ 0.5 ppm) and non-detectable solvent residues. Supplied as a pale tan micro-crystalline powder with 100% water solubility and thermal endurance up to 100°C, 5-HMF retains full active potency through steam conditioning, pelleting, and twin-screw extrusion. It exhibits outstanding chemical compatibility with vitamins, organic minerals, enzymes, and botanical extracts.

Direct procurement from Zhejiang Sugar Energy Technology Co., Ltd. grants commercial feed millers and functional additive blenders direct factory wholesale pricing, guaranteed bulk inventory security, and full technical dosage support. Partnering with our chemical plant empowers global nutrition enterprises to deliver high-value, functional feed formulations that maximize animal health and profitability.

Key Advantages

  • Delivers multi-target functional benefits: cellular ROS scavenging, hepatic metabolic support, and gut tight junction repair.
  • Reinforces gut mucosal epithelial integrity under environmental heat and stocking density stress.
  • Supports hepatic gluconeogenesis and prevents abnormal lipid accumulation in intensive production systems.
  • High thermal stability up to 100°C ensuring zero potency loss during feed pelleting and extrusion.
  • 100% bio-based active compound from renewable plant biomass, completely residue-free.

Quality & Compliance

  • ISO 9001 & ISO 22000 / GMP quality management system certification across synthesis facilities.
  • Batch-to-batch HPLC purity validation with official Certificate of Analysis (COA).
  • Strict heavy metal safety verification via ICP-MS analysis (Pb ≤ 3 ppm, As/Cd ≤ 0.5 ppm).
  • Non-GMO bio-derived chemical standard meeting global functional feed additive regulations.
  • Direct chemical manufacturer supply with complete export dossiers and technical support.
Property Unit Specification Test Method
Appearance — Light yellow to pale tan micro-powder Visual
Assay (5-HMF) % ≥ 98.0 HPLC-UV
Melting range °C 32 – 35 DSC
Water content % ≤ 1.0 Karl Fischer
pH (1% aqueous soln) — 4.5 – 6.5 pH Meter
Heavy Metals (as Pb) ppm ≤ 3 ICP-MS
Arsenic (As) ppm ≤ 0.5 ICP-MS
Cadmium (Cd) ppm ≤ 0.5 ICP-MS
Thermal Stability °C Up to 100 TGA

Market Outlook & Industry Trends

The global functional feed additive market is expanding rapidly as commercial livestock integrators seek targeted, bio-active solutions to replace prophylactic medications. Industry research projects the global functional feed additive market to rise from 11.2 billion USD in 2025 to 18.5 billion USD by 2032, achieving a compound annual growth rate (CAGR) of 7.4%.

Key growth drivers include rising demand for cellular antioxidants, increased focus on gut mucosal barrier protection, and tight environmental regulatory oversight on livestock waste emissions. 5-HMF provides functional feed formulators with a versatile, heat-stable active agent that delivers proven physiological health gains.

11.2B
2025 Market (USD)
18.5B
2032 Forecast (USD)
7.4%
CAGR 2026-2032
98%+
Factory HPLC Purity

5-HMF vs Synthetic Antioxidants vs Botanical Extracts: Functional Additive Comparison

Evaluating targeted bio-active molecules is crucial for functional feed formulators seeking high physiological efficiency. The table below compares functional-grade 5-HMF with Synthetic Antioxidants (BHT/Ethoxyquin) and Botanical Extract Blends across cellular ROS scavenging, mucosal tight junction repair, and heat stability.

Parameter 5-HMF (This Product) Synthetic Antioxidants (BHT / Ethoxyquin) Botanical Extracts (Polyphenols)
Active Mechanism Intracellular ROS scavenging & tight junction repair In vitro lipid oxidation inhibition Free-radical neutralization & antimicrobial
CAS / Classification 67-47-0 / Bio-active Molecule 128-37-0 (BHT) / Synthetic Chemical Botanical Extract Blends
Cellular Tight Junction Repair High — directly upregulates occludin/claudin None Moderate
Pelleting Thermal Stability High — stable up to 100 °C High thermal stability Low to Moderate — heat degradation
Regulatory & Tissue Residue Safety 100% Bio-based — zero residue, zero withdrawal Strict residue limits & EU bans Safe natural extracts
Bio-based / Renewable Origin 100% Renewable Biomass 0% (Petrochemical synthesis) Natural plant origin
Inclusion Rate Efficiency 50 to 300 g/t complete feed 100 to 200 g/t 200 to 1,000 g/t

Key takeaway: Functional 5-HMF extends beyond passive lipid oxidation control by actively repairing cellular tight junctions and supporting liver metabolism, providing a clean bio-derived alternative to synthetic antioxidants subject to regulatory restrictions.

Company Profile

Zhejiang Sugar Energy Technology Co., Ltd. (Sugar Energy Technology), established in 2017, is a national high-tech enterprise co-founded with participation from the Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences. As China 5-HMF For Functional Feed Additives Manufacturers and Wholesale 5-HMF For Functional Feed Additives Factory, focusing on the R&D, production and sales of bio-based furan new materials, the company leverages its advanced raw material production capabilities and downstream application innovation strengths to build a furan materials system of “1 high-end raw material + 5 platform molecules + N high-value products,” and aspires to become a leading bio-based materials enterprise driven by innovation and a strong sense of social responsibility.

Sugar Energy Technology’s flagship product, 5-hydroxymethylfurfural (HMF), is derived from a wide range of biomass feedstocks, including starch, cellulose, sucrose and agar. Featuring rare dual reactive functional groups and an aromatic structure, HMF not only helps improve the performance of other bio-based materials, but also opens up broader possibilities for the modification of conventional fossil-based products.

  • Company founding 2017
  • Annual output 2000 tons
  • Factory area 4500㎡
  • Invention patent 20+
  • HMF market share 70%
  • Technician 40+
Honor Of Sugar Energy Technology

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Frequently Asked Questions

What is 5-HMF and how does it function as a functional feed additive?
5-Hydroxymethylfurfural (5-HMF) is a bio-derived active compound synthesized from C6 sugars. As a functional feed additive, it acts as a cellular free-radical scavenger, liver protectant, and intestinal tight junction stabilizer across livestock and aquaculture species.
What is the recommended inclusion rate for 5-HMF in functional feed formulations?
Recommended inclusion rates range from 50 grams to 300 grams of pure 5-HMF per metric ton of complete finished feed, depending on physiological challenge level.
How does 5-HMF compare to synthetic antioxidants like BHT or Ethoxyquin?
Unlike synthetic chemical antioxidants that only prevent feed lipid oxidation, 5-HMF actively protects intracellular liver parenchymal cells and repairs gut mucosal tight junctions without residue risks.
Is 5-HMF stable during high-temperature feed pelleting and extrusion?
Yes. Our micro-crystalline 5-HMF possesses high thermal endurance up to 100°C, maintaining full active chemical potency throughout standard feed conditioning, steam pelleting, and extrusion.
Can 5-HMF be combined with vitamins, organic minerals, and plant extracts?
Yes. 5-HMF exhibits outstanding chemical compatibility when formulated with synthetic vitamins, organic mineral chelates, feed enzymes, and botanical extracts.
Does 5-HMF leave chemical residues in meat, milk, or egg products?
No. 5-HMF is 100% bio-based and biodegradable. It metabolizes cleanly in animal digestive systems, leaving zero harmful residues in tissue, requiring zero withdrawal period.
What animal species benefit most from functional feeds containing 5-HMF?
5-HMF is effective across broiler chickens, laying hens, swine (sows and nursery piglets), beef and dairy cattle, and high-density aquaculture species (shrimp and fish).
What quality management certifications cover Zhejiang Sugar Energy's production?
Our production operates under ISO 9001 and ISO 22000 / GMP quality management systems. Every batch is systematically verified via HPLC purity analysis and ICP-MS heavy metal testing.
What packaging sizes are available for commercial functional additive orders?
Standard export packaging includes 25 kg fiber drums with double foil vacuum liners and 500 kg woven super sacks on heat-treated wooden pallets. Custom OEM branding is fully supported.
How can commercial feed manufacturers request trial evaluation samples?
Commercial clients can contact our sales department to request trial evaluation samples (100g to 2kg). Samples dispatch via express air courier within 24 to 48 hours with complete COAs.
What are the international shipping and trade payment options?
We accept T/T (30% deposit, 70% against B/L copy), 100% L/C at sight, and D/P. Shipments dispatch from Ningbo or Shanghai deep-water ports under FOB, CFR, CIF, DDP, or DAP Incoterms with full customs dossiers.
Why partner directly with Zhejiang Sugar Energy Technology Co., Ltd.?
As a direct chemical synthesis manufacturer, we offer direct factory wholesale pricing, guaranteed bulk inventory security, active purity exceeding 98.0%, and expert technical formulation support.

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