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5-HMF For Aquaculture Feed Wholesale

5-HMF For Aquaculture Feed

High-purity bio-derived aquafeed active compound — engineered for shrimp & fish hepatopancreas protection and low FCR.
CAS 67-47-0 · Molecular Formula C₆H₆O₃ · MW 126.11
Purity

≥ 98.0%

  • HPLC Purity 98.6%
  • Moisture content ≤ 1.0%
  • Heavy metals (Pb) ≤ 3 ppm
Physical

Micro-crystalline

  • Melting point 32 – 35 °C
  • Water solubility 100% Dissolvable
  • Thermal endurance Stable to 100°C
Aqua Performance

Fish & Shrimp Grade

  • Inclusion rate 100 – 300 g/t
  • pH (1% soln) 4.5 – 6.5
  • Shelf life 24 Months

Product Overview

5-Hydroxymethylfurfural (5-HMF) for Aquaculture Feed is an advanced bio-active active compound manufactured by Zhejiang Sugar Energy Technology Co., Ltd. Specially engineered for intensive marine and freshwater aquaculture, including penaeid shrimp (Penaeus vannamei), tilapia, salmon, sea bass, and carp species, this bio-derived platform compound strengthens hepatopancreas functional capacity, fortifies intestinal mucosal tight junctions, and lowers overall Feed Conversion Ratio (FCR) in commercial aquafeed manufacturing.

Intensive aquaculture operations face mounting environmental challenges, including fluctuating water salinity, high stocking densities, pathogenic bacterial loads, and dietary shifts toward plant-protein meal substitutes. These stressors induce severe oxidative damage in the hepatopancreas and gut mucosa of aquatic animals, causing enterocyte sloughing, impaired digestive enzyme secretion, and elevated mortality. 5-HMF functions as a potent cellular free-radical scavenger, neutralizing ROS directly within mucosal epithelial cells and supporting endogenous antioxidant defense pathways.

When integrated into floating or sinking aquafeed pellets, 5-HMF preserves intestinal epithelial integrity, enhances intestinal villi height, and expands nutrient absorptive surface area. In shrimp culture, 5-HMF protects hepatopancreatic tubular cells, accelerates post-molting recovery, and improves survival rates during pathogenic Vibrio stress. Furthermore, it enhances fat and protein digestibility, enabling feed formulators to optimize dietary protein efficiency without compromising growth rates.

Zhejiang Sugar Energy Technology Co., Ltd. manufactures aquaculture-grade 5-HMF under strict ISO 9001 and ISO 22000 / GMP quality management protocols, ensuring zero heavy metal contamination (Pb ≤ 3 ppm, As/Cd ≤ 0.5 ppm) and non-detectable solvent residues. Supplied as a light yellow micro-crystalline powder with 100% water solubility and thermal endurance up to 100°C, 5-HMF maintains full chemical potency throughout high-pressure aquafeed conditioning, steam pelleting, and twin-screw extrusion. It demonstrates outstanding chemical compatibility with fish oils, binder hydrocolloids, organic acids, and immune stimulants.

Direct procurement from Zhejiang Sugar Energy Technology Co., Ltd. grants aquafeed manufacturers, commercial integrators, and premix formulators direct factory wholesale pricing, guaranteed bulk inventory security, and full regulatory compliance support. Partnering with our chemical synthesis facility empowers global aquaculture enterprises to achieve sustainable, antibiotic-free production goals while maximizing aquatic harvest yields worldwide.

Key Advantages

  • Protects shrimp and fish hepatopancreas tubular cells against oxidative damage and environmental stress.
  • Reinforces intestinal mucosal tight junctions, lowering aquafeed FCR by 3% to 6%.
  • Improves survival rates during post-molting periods in penaeid shrimp and reduces disease susceptibility.
  • High thermal endurance up to 100°C, fully resisting loss during high-temperature extrusion processing.
  • 100% bio-based compound derived from renewable biomass, leaving zero synthetic residues in water or aquatic tissue.

Quality & Compliance

  • ISO 9001 & ISO 22000 / GMP quality management compliance across manufacturing facilities.
  • Batch-to-batch HPLC purity validation with official Certificate of Analysis (COA).
  • Strict heavy metal safety compliance via ICP-MS testing (Pb ≤ 3 ppm, As/Cd ≤ 0.5 ppm).
  • Non-GMO renewable biomass origin complying with global aquaculture food safety regulations.
  • Direct chemical manufacturer wholesale supply with complete export dossiers and technical support.
Property Unit Specification Test Method
Appearance — Light yellow to pale tan micro-powder Visual
Assay (5-HMF) % ≥ 98.0 HPLC-UV
Melting range °C 32 – 35 DSC
Water content % ≤ 1.0 Karl Fischer
pH (1% aqueous soln) — 4.5 – 6.5 pH Meter
Heavy Metals (as Pb) ppm ≤ 3 ICP-MS
Arsenic (As) ppm ≤ 0.5 ICP-MS
Cadmium (Cd) ppm ≤ 0.5 ICP-MS
Thermal Stability °C Up to 100 TGA

Market Outlook & Industry Trends

The global aquafeed additive market is expanding rapidly, driven by the steady growth of farmed fish and crustacean production to meet worldwide protein demand. Industry market analyses project the global aquafeed additive sector to rise from 6.8 billion USD in 2025 to 11.4 billion USD by 2032, achieving a compound annual growth rate (CAGR) of 7.6%.

Key market growth drivers include rising commercial reliance on high-density aquaculture systems, elevated need for hepatopancreas protectors in high-plant-protein diets, and strict regulatory restrictions on antibiotic use in export waterbodies. 5-HMF provides aquafeed formulators with a bio-based, heat-stable active compound that enhances intestinal health and protects aquatic hepatopancreatic tissue without polluting aquatic habitats.

6.8B
2025 Market (USD)
11.4B
2032 Forecast (USD)
7.6%
CAGR 2026-2032
98%+
Factory HPLC Purity

5-HMF vs Synthetic Immunostimulants vs Organic Acids: Aquafeed Comparison

Comparing functional aquafeed active ingredients is essential for formulating high-performance fish and shrimp feeds. The table below compares aqua-grade 5-HMF with Beta-Glucan Immunostimulants and Organic Acid Salt Blends across hepatopancreas protection, extrusion heat endurance, and FCR optimization.

Parameter 5-HMF (This Product) Beta-Glucan Immunostimulants Organic Acid Salts (Potassium Diformate)
Active Mechanism ROS scavenging & gut mucosal tight junction repair Immune system stimulation (macrophage activation) Gut pH reduction & antibacterial buffer
CAS / Classification 67-47-0 / Bio-active Molecule 9004-54-0 / Polysaccharide 20642-05-1 / Organic Acid Salt
Hepatopancreas Cell Protection High — directly neutralizes oxidative ROS Moderate indirect effect Minimal direct impact
Extrusion Thermal Stability High — stable up to 100 °C Moderate — structural breakdown risk High thermal stability
Aquafeed FCR Reduction 3% to 6% Verified Gain 1% to 3% Gain 2% to 4% Gain
Water Solubility & Environmental Safety 100% Bio-based & Biodegradable Insoluble / hydrocolloid Soluble organic salt
Inclusion Rate Efficiency 100 to 300 g/t complete feed 500 to 2,000 g/t 2,000 to 5,000 g/t

Key takeaway: 5-HMF provides direct hepatopancreas and gut mucosal cell protection against oxidative stress in aquatic animals, outperforming beta-glucans in thermal extrusion stability and requiring far lower inclusion rates than high-dose organic acid salts.

Company Profile

Zhejiang Sugar Energy Technology Co., Ltd. (Sugar Energy Technology), established in 2017, is a national high-tech enterprise co-founded with participation from the Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences. As China 5-HMF For Aquaculture Feed Manufacturers and Wholesale 5-HMF For Aquaculture Feed Factory, focusing on the R&D, production and sales of bio-based furan new materials, the company leverages its advanced raw material production capabilities and downstream application innovation strengths to build a furan materials system of “1 high-end raw material + 5 platform molecules + N high-value products,” and aspires to become a leading bio-based materials enterprise driven by innovation and a strong sense of social responsibility.

Sugar Energy Technology’s flagship product, 5-hydroxymethylfurfural (HMF), is derived from a wide range of biomass feedstocks, including starch, cellulose, sucrose and agar. Featuring rare dual reactive functional groups and an aromatic structure, HMF not only helps improve the performance of other bio-based materials, but also opens up broader possibilities for the modification of conventional fossil-based products.

  • Company founding 2017
  • Annual output 2000 tons
  • Factory area 4500㎡
  • Invention patent 20+
  • HMF market share 70%
  • Technician 40+
Honor Of Sugar Energy Technology

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Frequently Asked Questions

What is 5-HMF and how does it benefit aquaculture feeds?
5-Hydroxymethylfurfural (5-HMF) is a bio-derived active compound synthesized from C6 sugars. In aquafeeds, it functions as a potent antioxidant, hepatopancreas protector, and gut mucosal stabilizer that lowers FCR in shrimp and fish.
What aquatic species can utilize 5-HMF feed additives?
5-HMF is formulated for marine and freshwater species, including penaeid shrimp (Vannamei), tilapia, salmon, trout, sea bass, sea bream, and commercial carp species.
What is the recommended inclusion rate for 5-HMF in commercial aquafeeds?
Recommended inclusion rates range from 100 grams to 300 grams of pure 5-HMF per metric ton of complete floating or sinking aquafeed.
How does 5-HMF protect the hepatopancreas in penaeid shrimp?
5-HMF neutralizes oxidative free radicals generated by environmental stress and high-plant-protein diets, preserving hepatopancreatic B-cells and tubule structure during molting and Vibrio stress.
Is 5-HMF stable during high-temperature twin-screw aquafeed extrusion?
Yes. Our micro-crystalline 5-HMF possesses high thermal endurance up to 100°C, maintaining full chemical potency throughout conditioning, steam pelleting, and extrusion processes.
Does 5-HMF leave chemical residues in fish or shrimp tissue?
No. 5-HMF is 100% bio-based and biodegradable. It metabolizes cleanly in the aquatic digestive system, leaving zero harmful residues in tissue, requiring zero withdrawal period.
Does 5-HMF pollute aquaculture pond water or aquatic ecosystems?
No. 5-HMF is derived from natural plant carbohydrates and degrades into harmless organic metabolites, posing zero risk of heavy metal or toxic chemical build-up in pond ecosystems.
Can 5-HMF be combined with fish oils, organic acids, and immune stimulants?
Yes. 5-HMF demonstrates excellent chemical compatibility when blended into premixes containing fish oil, organic acidifiers, essential oils, hydrocolloid binders, and beta-glucans.
What quality management certifications cover Zhejiang Sugar Energy's production?
Our production operates under ISO 9001 and ISO 22000 / GMP quality management systems. Every batch is systematically verified via HPLC purity analysis and ICP-MS testing.
What packaging sizes are available for commercial aquafeed orders?
Standard export packaging includes 25 kg fiber drums with double foil vacuum liners and 500 kg woven super sacks on heat-treated wooden pallets. Custom OEM labeling is fully supported.
How can commercial aquafeed manufacturers request trial evaluation samples?
Commercial clients can contact our sales department to request trial evaluation samples (100g to 2kg). Samples dispatch via express air courier within 24 to 48 hours with complete COAs.
Why partner directly with Zhejiang Sugar Energy Technology Co., Ltd.?
As a direct chemical synthesis manufacturer, we offer direct factory wholesale pricing, guaranteed bulk inventory security, active purity exceeding 98.0%, and expert technical dosage support.